Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis Descriptor: ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... Authors: Ramachandran, R, Shukla, A, Afsar, M. Deposit date: 2019-07-22 Release date: 2020-07-22 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
创建时间：
2019-07-22
