Objectives : It has been hypothesised that altered sensorimotor gating might be a core problem in Tourette Syndrome (TS). However, the underlying neurophysiological mechanisms are elusive. Me
This study investigates the role of TrkB in PV and SST interneurons and explores the validity of an interneuron-specific TrkB knockout mouse model. Mice with reduced TrkB expression in either PV-INs o