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Kidney spheroids generate a functional quiescent niche leading to enhanced tubulogenic potency of human kidney-derived cells

ChEBI2011-12-31 更新2026-07-21 收录

器官组织工程

细胞周期调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-28052 数据链接链接失效反馈

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Kidney spheroids generate a functional quiescent niche leading to enhanced tubulogenic potency of human kidney-derived cells

应用场景：

创建时间：

2011-12-31

细胞周期调控

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Cell fate determination in the asymmetric bacterium Caulobacter crescentus (Caulobacter) is triggered by the localization of the developmental regulator SpmX to the old (stalked) cell pole during the

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A kinase-phosphatase switch transduces environmental information into a bacterial cell cycle circuit. Caulobacter vibrioides

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The bacterial cell cycle has been extensively studied under standard growth conditions. How it is modulated in response to environmental changes remains poorly understood. Here, we demonstrate that th

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Arrest of G(1)-S Progression by the p53-Inducible Gene PC3 Is Rb Dependent and Relies on the Inhibition of Cyclin D1 Transcription

细胞周期调控

肿瘤抑制基因

The p53-inducible gene PC3 (TIS21, BTG2) is endowed with antiproliferative activity. Here we report that expression of PC3 in cycling cells induced accumulation of hypophosphorylated, growth-inhibitor

PubMed Central30

Additional file 16 of STAU2 protein level is controlled by caspases and the CHK1 pathway and regulates cell cycle progression in the non-transformed hTERT-RPE1 cells

细胞周期调控

蛋白相互作用分析

Additional file 16: Table S9. Gene ontology (GO) of STAU2 interactors that show reduced proximity to STAU2 in hTERT-RPE1 cells treated with the CHK1 inhibitor PF47 compared to untreated cells. List of

Figshare2021-03-05 更新60

CD38 enzymatic activity promotes hematopoietic stem cell dormancy [bulk RNA-Seq]

造血干细胞休眠

细胞周期调控

Quiescence is a fundamental property that protects hematopoietic stem cells’ (HSCs) function throughout life. A subpopulation of deeply quiescent, so-called dormant HSCs (dHSCs) harbors the highest lo

NIAID Data Ecosystem30

Kidney spheroids generate a functional quiescent niche leading to enhanced tubulogenic potency of human kidney-derived cells

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