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The role of C/ebp-alpha isoforms in myeloid differentiation

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https://www.ncbi.nlm.nih.gov/sra/ERP147118
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资源简介:
Genome wide ChIP-seq and RNA-seq (nascentRNA) study determining the global binding sites and target genes of Cebp-alpha isoforms p30 and p42 and of the downstream target Egr1. Primary hematopoietic cells pretransformed with either HoxA9 or MLL-ENL were transduced with inducible, degron-modified p42-FKBP, p30-FKBP, and Egr1-FKBP. Genomic binding was determined by ChIP-seq after protein induction. RNA inventory of the cells was recorded by nascentRNA seq in a time course after protein induction.
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2023-09-17
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