Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI Descriptor: CALCIUM ION, DNA (26-MER), I-OnuI_e-vHIVInt_v2 Authors: Stoddard, B.L, Werther, R, Lambert, A.R. Deposit date: 2016-09-07 Release date: 2017-05-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. Protein Eng.Des.Sel., 30, 2017
创建时间：
2016-09-07
