Genome-wide profiling of gene expression under electro-acupuncture pretreatment on myocardial I/R injury in rats

Conclusions: Our results for the first time generated genome-wide gene expression profiles both in the rat I/R model and in acupuncture treatment by high throughput sequencing. The optimized data analysis workflows reported here should provide a framework for acupuncture investigations of expression profiles.结论：本研究首次通过高通量测序（high throughput sequencing）技术，成功构建了大鼠缺血再灌注（ischemia/reperfusion, I/R）模型与针刺干预两组样本的全基因组基因表达谱（genome-wide gene expression profiles）。本文所报道的优化数据分析流程，可为针刺相关基因表达谱研究提供标准化分析框架。