One-way sensitivity analyses—cost per DALY averted.

All costs in US dollars. Incremental cost-effectiveness thresholds obtained in one-way sensitivity analyses were calculated by replacing the base case estimates of a single parameter in the model with a very high and a very low value, while leaving all other model parameters unchanged. For space considerations, Table 4 reports only the upper end of the new ICER range.aNo 95% confidence interval was available for these parameters; we therefore used a subjective range for syphilis prevalence and nurse wages, and looked to cost estimates cited in other published sources to inform the sensitivity range for the ICS test and the cost of penicillin therapy.bThe sensitivity range was informed by 95% confidence intervals around the base case estimate.cThe sensitivity range of the discount rate followed WHO guidance [16].RR, relative risk.