Summary of adverse events in Part 1 (SD) and Part 2 (RD).
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https://figshare.com/articles/dataset/_Summary_of_adverse_events_in_Part_1_SD_and_Part_2_RD_/1030958
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*Only those occurring in ≥4 subjects across all cohorts are listed.
†Five unreported AEs were identified (in 3 subjects): 1 subject experienced severe diarrhea (2.5 mg/kg), 1 subject experienced shoulder pain, secondary to muscle biopsy (15 mg/kg), and 1 subject experienced some minor skin bruising, a fall and a hard swelling on the left hip (resulting from the fall) (15 mg/kg).
**Two doses, received 4 weeks apart.
‡Only those occurring in ≥2 subjects across all cohorts are listed. AE, adverse event; n, number of subjects; SD, single dose; RD, repeated dose.
创建时间:
2014-05-19



