DACD rats intervened by fecal microbiota transplantation

The current study aims to investigate whether n-3 PUFA can affect the kind and quantity of gut microbiota by dietary intervention, thereby reducing peripheral inflammation, which in turn improves central nervous system inflammation and ultimately reduces symptoms of DACD. Furthermore, the presence of gut microbiota as a mediator of the ameliorative effect of n-3 PUFA on DACD was confirmed through the use of fecal microbiota transplantation.