A collection of high-quality human assemblies

A collection of high-quality human assemblies, including: T2T-CHM13 v2.0 analysis set with HG002 chrY and rCRS chrM GRCh38 no-alt analysis set with rCRS chrM HG002 v1.1 CN1 v1.0.1 YAO v1.1 195 HPRC "r2" samples (390 assemblies, excluding HG00272) Use AGC to extract indivual genomes and use ropebwt3 to query the FM-index: agc listset human398.agc # list genomesagc getset human398.agc 400131_HG02615.pat > HG02615.pat.fa # extract one genomegzip -d human398.fmr.gz # decompress the incremental indexropebwt3 build -i human398.fmr -do human398.fmd # convert to a faster query formatgzip -d human398.fmd.ssa.gz # decompress suffix array samplesecho CCAGGACCCCTGTCCAGTGTTAGACAGGAGCATGCAG | ropebwt3 sw -eN200 -Lm10 human398.fmd - Note: The HPRC assemblies are already available from GenBank. This repository only provides a convenient way to download them. However, these assemblies are not formally published. You may use them for algorithm development or performance evaluation. If you want to use the genomes for biological discovery, please contact HPRC.