CircRNA expression-profiling to predict prognosis in locoregionally advanced nasopharyngeal carcinoma. CircRNA expression-profiling to predict prognosis in locoregionally advanced nasopharyngeal carcinoma

CircRNAs serve as prognostic biomarkers in various types of cancer. We aimed to identify a circRNA signature for individual relapse risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC). Overall design: Using Agilent SurePrint G3 Custom GE 4x180K Microarray, we profiled the circRNA expression in tissues between 5 normal nasopharyngeal tissues and 25 NPC tissues, among which 8 tissues from patients with recurence and distant metastasis after radical treatment.