Crystal Structure of the first bromodomain of human BRD4 in complex with a 3-chloro-pyridone ligand
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal Structure of the first bromodomain of human BRD4 in complex with a 3-chloro-pyridone ligand Descriptor: 3-chloro-5-[1-(3-methylpyridin-2-yl)-3-phenyl-1H-1,2,4-triazol-5-yl]pyridin-2(1H)-one, Bromodomain-containing protein 4 Authors: Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, Vidler, L.R, Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Hoelder, S, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2013-08-27 Release date: 2013-09-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. J.Med.Chem., 56, 2013
创建时间：
2013-08-27
