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Organocatalytic Sequential α-Amination−Horner−Wadsworth−Emmons Olefination of Aldehydes: Enantioselective Synthesis of γ-Amino-α,β-Unsaturated Esters

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https://figshare.com/articles/dataset/Organocatalytic_Sequential_Amination_Horner_Wadsworth_Emmons_Olefination_of_Aldehydes_Enantioselective_Synthesis_of_Amino_Unsaturated_Esters/3019030
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资源简介:
A novel and highly enantioselective method for the synthesis of γ-amino-α,β-unsaturated esters via tandem α-amination−Horner−Wadsworth−Emmons (HWE) olefination of aldehydes is described. The one-pot assembly has been demonstrated for the construction of functionalized chiral 2-pyrrolidones, subunits present in several alkaloids.
创建时间:
2007-03-15
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