Whole cell patch-clamp recordings of cerebellar granule cells

This dataset provides a characterization of the intrinsic excitability and synaptic properties of the cerebellar granule cells. Whole-cell patch-clamp recordings were performed on acute parasagittal cerebellar slices obtained from juvenile Wistar rats (p18-p24). Passive granule cells parameters were extracted in voltage-clamp mode by analyzing current relaxation induced by step voltage changes (IV protocol). Granule cells intrinsic excitability was investigated in current-clamp mode by injecting 2 s current steps (CC step protocol). Synaptic transmission properties were investigated in current clamp mode by an electrical stimulation of the mossy fibers bundle (5 pulses at 50 Hz, EPSP protocol).