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Biofilm Formation and Virulence of Shigella flexneri is Modulated by pH

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE183515
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In this study, we probed factors that could influence Shigella pathogenesis. We show that in basic pH conditions, deoxycholate-induced biofilm formation and virulence of Shigella are attenuated. We utilized RNA-sequencing to investigate pathways enriched in bacterial cells in biofilms. Transcriptomic profiles of Shigella in different conditions of growth.
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2021-12-09
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