Effects of loss of the histone lysine acetyltransferase KAT7 on mRNA levels in proliferating and differentiating mouse neural stem cells (neurosphere cells) [RNA-seq]

RNA-seq data of neural stem and progenitor cell (NSPC) isolates from Kat7lox/loxNesCreT/+ and Kat7+/+NesCreT/+ E14.5 foetuses for each, proliferating and differentiating conditions. KAT7 and H3K14ac were not required for the continued transcription of genes that were actively transcribed at the time of loss of KAT7, but indispensable for the activation of repressed genes. Overall design: RNA-seq data of NSPC isolates from 4 Kat7lox/loxNesCreT/+ and 4 Kat7+/+NesCreT/+ E14.5 foetuses for each, proliferating and differentiating conditions. NSPC isolates were kept in proliferating conditions for 3 passages and 3 days or differentiated for 3 days after passage 3.