Experimental data of C38 mouse colon adenocarcinoma (tumor length, tumor width, tumor mass and tumor volume).

Data was measured at the final day of Phase I (24th day) and Phase III/3 (23rd day).a Directly measured data (tumor length, tumor width, tumor mass)b Estimated data (tumor volume measured by caliper, calculated according to Xenograft tumor model protocol or two-dimensional mathematical model)c MRI-measured data (tumor volume calculated with flood fill algorithm)d Evaluated data (“MRI” tumor volume calculated from linear curve fit (see Eq 8))Experimental data of C38 mouse colon adenocarcinoma (tumor length, tumor width, tumor mass and tumor volume).