Additional file 1 of Spatial intra-tumour heterogeneity and treatment-induced genomic evolution in oesophageal adenocarcinoma: implications for prognosis and therapy

Additional file 1: Table S1. Clinical information for the cohort. NSR, no sign of recurrence; OG, oesophago-gastric. Table S2. Sample information including estimated tumour cellularity, mutation count and tumour mutation burden (TMB; mutations/Mb). Table S3. Differences in signature proportions between shared and private mutation populations. Comparisons between continuous values used Student’s t-test and Fisher’s exact test for dichotomised data. p-values were corrected for multiple testing through fdr correction. Table S4. Detected clonal ClinVar variants in TP53 across the cohort. Table S5. Number of mutations assigned to individual clones. Table S6. Putative neoantigens identified in clones present in pre-treatment but not post-treatment samples.