Microbiota Contributes to Celastrol Protection against Obesity through Enhancement of Energy Expenditure

Obesity and numerous related complications are getting great risk threatening the global health. Due to the socio-economic burden of these diseases, effective prevention and treatment strategies are definitely crucial to halt obesity epidemic. Natural plant-derived biomolecules constitute a great source for seeking potential therapeutic candidates, and we conducted the research in order to define the anti-obesity effect of celastrol.