Niche stiffening compromises stem cell potential during aging by reducing chromatin accessibility at bivalent promoters

RNA and ATAC sequencing data of CD34+ Ia6+ sorted hair follicle stem cells from 6 and 24 months old mice Total RNA from 3 biological replicates of CD34+ Ia6+ sorted hair follicle stem cells from 6 and 24 months old mice . Paired-end sequencing 150bp reads HiSeq3000. ATAC-seq from 4 biological replicates of sorted hair follicle stem cells from 6 and 24 months old mice. Paired-end sequencing 75bp reads HiSeq4000. H3K27me3 ChIP-seq from 3 biological replicates, and H3K4me3 and Pol2 ChIP-seq from 2 biological replicates of sorted hair follicle stem cells from 6 and 24 months old mice. Paired-end sequencing 100bp reads NovaSeq6000.