Bsn

ENCODES a protein that exhibits dynein light chain binding; enzyme inhibitor activity; transcription corepressor binding; INVOLVED IN axo-dendritic transport; modulation of chemical synaptic transmission; presynaptic active zone assembly; ASSOCIATED WITH Aicardi-Goutieres Syndrome 1 (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN axon cytoplasm; cell cortex; cytoskeleton of presynaptic active zone; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil

编码一种具有动力蛋白轻链结合能力、酶抑制活性、转录共抑制因子结合能力的蛋白质；参与轴突-树突运输、化学突触传递的调节、突触前活性区组装；与Aicardi-Goutieres综合征1（同源物）、发育性和癫痫性脑病（同源物）、早期婴儿期癫痫性脑病（同源物）相关；存在于轴突细胞质、细胞皮质、突触前活性区细胞骨架中；与2,3,7,8-四氯二苯并-对-二噁英、4-氨基-2,6-二硝基甲苯、6-丙基-2-硫尿嘧啶相互作用。