High dose IFN-𝛽 activates GAF to enhance expression of ISGF3 target genes in epithelial cells. High dose IFN-𝛽 activates GAF to enhance expression of ISGF3 target genes in epithelial cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA678362
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资源简介:
GAF is transcriptionally inactive in epithelial cells but enhances expression of ISGF3 target genes, thus functioning as a dose-sensitive amplifier of the IFN-𝛽 response. Overall design: Sequencing data from MLE-12 murine lung epithelial cell line, stimulated with interferon 𝛽 or 𝛾: STAT1 ChIP-seq (19 samples), mRNA-seq (53 samples).
创建时间:
2020-11-13



