Comparative transcriptomics allows defining mononuclear phagocyte subset homology across vertebrate species (Sheep). Ovis aries

Characterization of sheep blood and splenic immunocyte subpopulations by means of global expression analysis Overall design: We analysed the gene expression of blood plasmacytoid dendritic cells (DC) from 3 control sheep, blood SIRPa+ conventional DC (cDC) from 3 control sheep, blood CADM1+ cDC from 1 control sheep, splenic B lymphocytes from 4 control sheep, splenic monocytes/macrophages from 3 control sheep and Monocyte-derived DC from 3 independent in vitro cultures