Data from: A lateral flow strip based on gold nanoparticles to detect 6-monoacetylmorphine in oral fluid
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https://datadryad.org/dataset/doi:10.5061/dryad.8r36rp3
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资源简介:
We used lateral flow strips (LFS) based on gold nanoparticles (AuNPs) to
detect 6-monoacetylmorphine (6-MAM; heroin’s unique metabolite) in oral
fluid samples. In this competitive lateral chromatographic immunoassay,
the 6-MAM was chemically synthesized and conjugated to bovine serum
albumin (BSA). The results were qualitatively detected via the color
change of the test line. By using a proper sample pad, a suitable NC
membrane and a customized sponge device adsorbed the oral fluid directly
from mouth, and total test time was 3 minutes. The sensitivity of the
assay was 4.0 ng ml-1 without any cross-reactivity with ten normal drugs,
which are widely subject to abuse, including morphine and codeine. This
test could be easily used on site to detect heroin in oral fluid, and it
could be a promising product in the future including for driving under the
influence.
提供机构:
Dryad
创建时间:
2018-05-22



