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Substituted 2-Naphthamidine Inhibitors of Urokinase

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Substituted 2-Naphthamidine Inhibitors of Urokinase Descriptor: 6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE, Urokinase-type plasminogen activator Authors: Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. Deposit date: 2003-03-28 Release date: 2003-09-30 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
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2003-03-28
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