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CRYSTAL STRUCTURE OF PORCINE PANCREATIC ELASTASE WITH MDL 101,146

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Protein Data Bank Japan2024-12-25 更新2026-03-21 收录
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CRYSTAL STRUCTURE OF PORCINE PANCREATIC ELASTASE WITH MDL 101,146 Descriptor: 1-{3-METHYL-2-[4-(MORPHOLINE-4-CARBONYL)-BENZOYLAMINO]-BUTYRYL}-PYRROLIDINE-2-CARBOXYLIC ACID (3,3,4,4,4-PENTAFLUORO-1-ISOPROPYL-2-OXO-BUTYL)-AMIDE, CALCIUM ION, PROTEIN (ELASTASE) Authors: Schreuder, H.A, Metz, W.A, Peet, N.P, Pelton, J.T, Tardif, C. Deposit date: 1998-11-09 Release date: 1998-11-18 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones. J.Med.Chem., 41, 1998
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1998-11-09
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