RNA interference (RNAi) is a gene silencing mechanism conserved from fungi to mammals. Small interfering RNAs are products and mediators of the RNAi pathway and act as specificity factors in recruitin

NIAID Data Ecosystem30

Regulation of mRNA Levels by Suicidal Introns that Induce Nuclear Decay. Schizosaccharomyces pombe

RNA降解机制

裂殖酵母基因调控

In eukaryotic cells, inefficient splicing is surprisingly common and leads to degradation of transcripts with retained introns. How pre-mRNAs are committed to nuclear decay is unknown. Here we uncover

NIAID Data Ecosystem20

The Cell Cycle–Regulated Genes of Schizosaccharomyces pombe

细胞周期转录

裂殖酵母基因调控

Many genes are regulated as an innate part of the eukaryotic cell cycle, and a complex transcriptional network helps enable the cyclic behavior of dividing cells. This transcriptional network has been

NIAID Data Ecosystem50

The fission yeast Schizosaccharomyces pombe: H3K9me2, Erh1-GFP and CFP-Mmi1 ChIP-chip. Schizosaccharomyces pombe

表观遗传修饰

裂殖酵母基因调控

ChIP-chip analyses of H3K9me2 (in WT, erh1∆, mmi1∆ and ccr4∆), Erh1-GFP (in WT and mmi1∆) and CFP-Mmi1 (in WT) Overall design: H3K9me2: WT vs erh1∆, WT vs mmi1∆ and WT vs ccr4∆; Erh1-GFP: WT vs mmi1∆;

NIAID Data Ecosystem30

S. pombe acetyltransferase mutants identifies redundant pathways of gene regulation, dual-channel dataset

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