THPdb: Database of FDA-approved peptide and protein therapeutics

THPdb: Database of FDA-approved Peptide and Protein Therapeutics Welcome to the official repository and documentation overview for THPdb, a manually curated repository of Food and Drug Administration (FDA) approved therapeutic peptides and proteins. This resource provides a comprehensive platform for researchers to explore clinical therapeutics, their drug variants, and their pharmacological profiles to assist in drug discovery. Web Server: http://crdd.osdd.net/raghava/thpdb/ Git Hub: https://github.com/sudhanshus-hash/THPdb Citation Usmani, S. S., Bedi, G., Samuel, J. S., Singh, S., Kalra, S., Kumar, P., ... & Raghava, G. P. S. (2017). THPdb: Database of FDA-approved peptide and protein therapeutics. PLOS ONE, 12(7): e0181748. https://doi.org/10.1371/journal.pone.0181748 About the Database THPdb was developed to provide the first single, freely available platform dedicated entirely to US-FDA approved protein and peptide therapeutics. It addresses the need for integrated data that was previously scattered across literature and disparate repositories. The database integrates data from: Primary Literature: Information compiled from 985 research publications and 70 patents. External Repositories: Data integrated from resources like DrugBank and the Protein Data Bank (PDB).