Crystal Structure of Human B-raf bound to a DFG-out Inhibitor 5B
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Crystal Structure of Human B-raf bound to a DFG-out Inhibitor 5B Descriptor: N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf Authors: Yano, J.K, Masanori, O. Deposit date: 2013-05-17 Release date: 2013-07-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives. J.Med.Chem., 56, 2013
创建时间：
2013-05-17
