iCAT: Diagnostic Assessment Tool for Immunological History using High-Throughput TCR Sequencing

The project focus was the development of a stream-lined application for the computational identification of pathogen-associated TCR sequences and the building of a diagnostic classifier capable of diagnosing prior pathogen exposure based on the present or absence of the pathogen-associated TCR sequences. This data is TCR sequencing data previously described in by Wolf et al (Wolf. Cell Reports. 2018, https://www.ncbi.nlm.nih.gov/pubmed/30485806).