DataSheet1_Efficient Synthesis of 2,3′-Spirobi (Indolin)-2′-Ones and Preliminary Evaluation of Their Damage to Mitochondria in HeLa Cells.PDF
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https://figshare.com/articles/dataset/DataSheet1_Efficient_Synthesis_of_2_3_-Spirobi_Indolin_-2_-Ones_and_Preliminary_Evaluation_of_Their_Damage_to_Mitochondria_in_HeLa_Cells_PDF/19217973
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资源简介：
A novel formal (4 + 1) annulation between N-(o-chloromethyl)aryl amides and 3-chlorooxindoles through in situ generated aza-ortho-QMs with 3-chlorooxindoles is reported for the synthesis of a series of 2,3′-spirobi (indolin)-2′-ones in high yields. Under structured illumination microscopy, compound 3a is found to change the mitochondrial morphology and induce mitophagy pathway, which might then trigger mitophagy in cancer cells.
创建时间：
2022-02-23
