Sequence identity among the precursor peptides vs. the number of LanM.

A comparison of the sequence identity of the precursor peptides identified in this study, including those of the well-known lantibiotics, bhtA, smb, lacticin 3147, haloduracin, staphylococcin C55, lichenicidin, procAs and cytolysin with the number of LanM processing enzymes required. Upto ∼20% sequence identity among the precursor peptides, two LanMs are required and 37% and above, a single LanM is sufficient for the processing.