Transcriptome analysis of E. coli strain MG1655 on exposure to glutathione (GSH) and/or ciprofloxacin

Expression profiling of wild type E. coli K-12 strain MG1655 with exogenous glutathione (GSH) supplementation, sub-inhibitory ciprofloxacin concentration and GSH with inhibitory ciprofloxacin concentration. We used microarrays to detail the global gene expression program underlying ciprofloxacin exposure and glutathione mediated abrogation of ciprofloxacin's anti-bacterial action. An eight-chip study with one E. coli strain under four separate culture conditions (two biological replicates for each condition).