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Crystal Structure of human PIN1 complexed with covalent inhibitor

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal Structure of human PIN1 complexed with covalent inhibitor Descriptor: 4-((5-bromofuran-2-yl)methyl)-8-(2-chloroacetyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Authors: Liu, L, Li, J, Zhu, R, Pei, Y. Deposit date: 2021-03-23 Release date: 2022-02-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1). J.Med.Chem., 65, 2022
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2021-03-23
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