Replication data for Colorectal cancer initiation by benzo[a]pyrene and N-nitroso compounds in A/J Min/+ mice

The dataset contains the complete raw data for the results presented in the manuscript Colorectal cancer initiation by benzo[a]pyrene and N-nitroso compounds in A/J Min/+ mice. The raw data were obtained from A/J Min/+ mice dietary exposed to individual or combined benzo[a]pyrene and n-nitroso compounds (NOCs) at low or high doses.
The main objective of the study was to characterize the carcinogenic potential of single or combined exposure to BaP and NOCs in the A/J Min/+ mouse model for colorectal cancer. The data includes various weights and lengths measurement, scoring of lesions in the small and large intestine , histopathology of lesions larger than 0,1962mm2 in the colorectum, and targeted plasma metabolomics. The aim was achieved by macroscopic investigations of intestinal tissue and histopathological characterization using light microscopy, in addition to targeted metabolomics of blood plasma using the p400 Biocrates kit.