Compensatory IKKa activation of classical NF-kB signaling during IKKb inhibition
收藏ChEBI2009-06-01 更新2026-07-21 收录
下载链接:
https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-11902
下载链接
链接失效反馈官方服务:
资源简介:
Compensatory IKKa activation of classical NF-kB signaling during IKKb inhibition
应用场景:
创建时间:
2009-06-01
相关数据集
In this project we have performed a miRNOme analysis of CF cells from CF patients cultured in air-liquid interface compared to non-CF cells cultured in the same condition.
Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thic
NIAID Data Ecosystem70
Interaction of the TNFR-Receptor Associated Factor TRAF1 with I-Kappa B Kinase-2 and TRAF2 Indicates a Regulatory Function for NF-Kappa B Signaling
BackgroundI-kappa B kinase 2 (IKK2 or IKK-beta) is one of the most crucial signaling kinases for activation of NF-kappa B, a transcription factor that is important for inflammation, cell survival and
NIAID Data Ecosystem70
Knockdown of REGγ inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-κB signal pathway
Objectives: This study aimed to evaluate the effects of REGγ knockdown on the proliferation, apoptosis and migration of multiple myeloma (MM) cells, and reveal the potential regulatory mechanisms. Me
NIAID Data Ecosystem60
Cleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF-{kappa}B Activation
Proper regulation of nuclear factor κB (NF-κB) transcriptional activity is required for normal lymphocyte function, and deregulated NF-κB signaling can facilitate lymphomagenesis. We demonstrate that
NIAID Data Ecosystem70
Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling
Persistent activation of NF-κB by the Human T-cell leukemia virus type 1 (HTLV-1) oncoprotein, Tax, is vital for the development and pathogenesis of adult T-cell leukemia (ATL) and HTLV-1-associated m
NIAID Data Ecosystem70



