MBOAT7 loss of function in clear cell Renal Carcinoma (ccRCC)
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE131881
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We demonstrated an increase in MBOAT7 and downstream phosphatidylinositol products in ccRCC. This RNAseq was of two loss of function clones and wild-type in the Caki-1 cell model (ccRCC cell line). We used CRISPR/Cas9 to generate knockout cell lines validated using Sanger and Western Blotting. The knockout clones were then RNA sequenced against a wild-type counterpart.
创建时间:
2020-02-26



