Mouse Dspp frameshift model of human dentinogenesis imperfecta
收藏DataCite Commons2021-10-23 更新2024-07-13 收录
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https://www.facebase.org/chaise/record/#1/isa:dataset/RID=5-J8R6
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资源简介：
Using CRISPR/Cas9, we generated a _Dspp_^−1fs^ mouse model by introducing a FLAG-tag followed by a single nucleotide deletion that translated 493 extraneous amino acids before termination. Developing incisors and/or molars from this mouse and a _Dspp_^P19L^ mouse were characterized by morphological assessment, bSEM, nanohardness testing, histological analysis, in situ hybridization and immunohistochemistry.
提供机构：
FaceBase (www.facebase.org)
创建时间：
2021-10-23
