Additional file 1 of Unraveling the causality between gastroesophageal reflux disease and increased cancer risk: evidence from the UK Biobank and GWAS consortia

Additional file 1: Table S1. Overview of data. Table S2. All-selected SNPs in the study. Table S3. Mendelian randomization analysis of GERD association with pan-cancer risk. Table S4. 63 unique potential confounding SNPs. Table S5. Sensitivity analysis for GERD and cancer. Table S6. Outlier analysis and correction of SNPs. Table S7. Reverse MR analysis of cancer on GERD. Table S8. Comparison of effects before and after adjusting variables. Table S9. Mendelian randomization analysis of the major depression, BMI, and smoking initiation association with pan-cancer risk. Table S10. Results from a two-step Mendelian randomization mediation analysis.