IL-4-mediates Pro-Regenerative Cellular Reprogramming in 3D Liver Culture
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP467030
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资源简介：
This study highlights the proregenerative effects of interleukin-4 in a 3-dimensional liver tissue culture platform. Interleukin-4 supplementation induces a myeloid cell phenotype shift, expands hepatocyte and cholangiocyte progenitors and inhibits fibroblast activation. Our findings open new avenues for cytokine-based therapies to stimulate immune-driven liver regeneration. Overall design: Single nucleus RNA sequencing of live nuclei in murine precision cut liver slices by high throughput sequencing
创建时间：
2025-09-27
