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m6A-sequencing of Mettl14-conditional knock-out retinas and matched control.

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP379895
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资源简介:
Post-transcriptional m6A methylation on mRNA plays a key role in neural development. Here, we specifically depleted Mettl14 (a key component of m6A complex) in retina progenitor cells by crossing Mettl14 fl/fl mice with the Chx10-Egfp/Cre mouse line and investigated Mettl14 depletion-induced m6A alteration in developing retinas using m6A-seq. Overall design: Immunoprecipitation of m6A-enriched mRNAs (m6A-seq) for control and Mettl14 cKO retinas.
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2023-09-01
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