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This special issue responds to the need for an in-depth investigation of activism and agency and brings to light translation work and translation networks created to support a culture of change across the world. It aims to celebrate the values and the principles endorsed and validated by activist translators and/or networks. The volume welcomes the cross-pollination with a number of disciplines, including but not limited to Translation Studies, Gender Studies, Migration and Mobility Studies, Cultural and Media Studies, Sociology, Ethnography, Politics, Linguistics and Literary Criticism among others. Besides its overview of the growing diversity of research (both theoretical and practical) on translation, this volume has a thematic orientation focused on the role played by translation as agent of resistance and change of the dynamics between gender, class, race and power, the human and the other-than-human in society.