Analysis of genes associated with MYC in maintaining tumorigenesis
收藏官方服务：
资源简介：
Analysis of genes associated with MYC in maintaining tumorigenesis
应用场景：
创建时间：
2008-08-28
相关数据集
Gene expression profiling in mouse fibroblast tumors with overexpression of the homeoprotein SIX1
Six1 is a developmental transcriptional regulator frequently overexpressed in human tumors. Recent results also show that SIX1 acts as a repressor of cell senescence, an antiproliferative response wit
NIAID Data Ecosystem110
Transcriptome changes following loss of Apc in the intestine. Mus musculus
Nearly all colorectal cancers have dysregulated Wnt signalling, predominantly through the mutation of the Apc (Adenomatous Polyposis Coli) gene. Therefore it is of vital importance to elucidate the ke
NIAID Data Ecosystem40
Gene expression profiling of preneoplastic Lgr5-creERT2/PIK3CAH1047R mammary subsets
This study examined the effect of mutant PIK3CAH1047R expression in mammary subsets of preneoplastic mammary glands from Lgr5-creERT2/PIK3CA H1047R mice Mammary cell subpopulations were isolated from
NIAID Data Ecosystem30
p53 amyloid formation induced cellular transformation and tumor formation in xenograft model
p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.
NIAID Data Ecosystem50
Expression of FUS-CHOP fusion protein in immortalized/transformed human Mesenchymal Stem Cells drives mixoid liposarcoma formation
Although different sarcomas have been modeled in mice upon expression of fusion oncogenes in MSCs, sarcomagenesis has not been successfully modeled in human MSCs (hMSCs). We report that FUS-CHOP, a ha
NIAID Data Ecosystem40
