Identification of genomic regions regulated by the Xrn1 and Upf1 proteins

Comparison of WT, xrn1 delta and upf1 delta strains were used in a tiling array to yield genomic regions regulated by these proteins The supplementary CHP files record either the signal in log2 space or the p-values in linear space, per TAS output本研究针对野生型（Wild Type, WT）、xrn1缺失突变株及upf1缺失突变株开展对比分析，采用平铺式基因芯片（tiling array）技术，最终鉴定得到受上述蛋白调控的基因组区域。补充材料中的CHP文件按照TAS的输出格式，分别记录了对数2空间下的信号值与线性空间下的p值。