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Crystal Structure of Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Complexed with GBT Compound 6

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal Structure of Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Complexed with GBT Compound 6 Descriptor: 5-[(imidazo[1,2-a]pyridin-8-yl)methoxy]-2-methoxypyridine-4-carbaldehyde, CARBON MONOXIDE, Hemoglobin subunit alpha, ... Authors: Partridge, J.R, Choy, R.M, Li, Z, Metcalf, B. Deposit date: 2017-01-04 Release date: 2017-02-22 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett, 8, 2017
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2017-01-04
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