Expression data from the complex I mutant gas-1 (fc21) C. elegans worms in comparison to wildtype N2 Bristol worm and under the inluence combination drug therapy

We studied genome-wide expression profiles of C. elegans young adult worms, complex I mutant gas-1(fc21) compare to the wild type N2 Bristol worm and the effect of combination drug treatment on the gene expression profile in gas-1(fc21). Overall design: 4 biological replicates of wildtype (N2 Bristol) synchronized worms grown on OP50 bacteria, 4 biological replicates of the complex I mutant C. elegans synchronized young adults and 4 biological replicates of synchronized complex I mutant worm treated with the different drug combination were used as sources of total RNA. Comparison of the data was intended to reveal causes of different antioxidant drug treatment on gene expresssion profile in the complex I mutant gas-1(fc21) worms.