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Transcriptome analysis of tumor-specific CD8 T cells in murine solid tumors. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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RNAseq analysis of CD8 T cells becoming dysfunctional in progressing tumors. The overall goal of this study was to elucidate the molecular program that mediates functional unresponsiveness in tumor-specific CD8 T cells. In comparison, we also investigated CD8 T cells differentiating to functional effector and memory T cells during an acute listeria infection. Overall design: T cells were sorted by flow cytometry and RNA-seq was performed.

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2016-10-29
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