Host response to the different pathologic conditions. Homo sapiens

The experiment adresses primary material from pneumonia, malaria, COPD and healthy patients. The transcriptome anaylsis shall shed light on the host response to the different pathologic conditions and hightlight key differences. Investigated cells (PBMCs) were obtained from patient blood by gradient centrifugation. Overall design: RNA from peripheral blood mononuclear cells was isolated from human subjects from four groups: heathly, pneumonia, COPD, and with Malaria infection, and subjected to one-color microarray analysis.