Loss-of-function mutations of p16(INK4a) have been identified in a large number of human tumors. An established biochemical function of p16 is its ability to specifically inhibit cyclin D-dependent ki
ChIP-Seq was carried out to map the genome-wide chromatin occupancy of ZNF148 in a basal subtype triple negative breast cancer cell-line, MDA-MB-231. Overall design: MDA-MB-231 cells stably expressing
Here We have performed sequencing of 412 cancer gene panel in 5 PDAC ad 3 PAC tumour blood paired sample. We used Hiseq2500 platform to generate 100 bp pair end reads. We have identified total 48 soma
N, normal adjacent tissue; T, tumor tissue. For RT qPCR (PCR) data: −, undetectable amounts of mRNA; +, detectable mRNA expression; +#, high amounts of mRNA. For Western (W) analysis: −, not detected;