PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells

ChEBI2015-09-16 更新2026-07-12 收录

子宫内膜蜕膜化

细胞周期同步调控

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PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells

创建时间：

2015-09-16

Seminal plasma promotes decidualization of endometrial stromal fibroblasts from women with and without inflammatory disorders in a manner dependent on IL11 signaling

子宫内膜蜕膜化

内分泌研究

SP promotes decidualization of eSF from women with and without inflammatory disorders (polycystic ovarian syndrome (PCOS), endometriosis) in a manner that is not mediated through semen amyloids and th

NIAID Data Ecosystem60

TRIM28 modulates progesterone and estrogne signaling in endometrium [mouseD3.5-RNAseq-mm10]. TRIM28 modulates progesterone and estrogne signaling in endometrium [mouseD3.5-RNAseq-mm10]

子宫内膜蜕膜化

类固醇信号传导

TRIM28 interacts with PGR and ESR1 in both human and mouse uterus to modulate estrogen and progesterone signaling. Knocking down of TRIM28 in the human endometrial stromal cells imparied decidualizati

NIAID Data Ecosystem50

Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss

复发性流产

子宫内膜蜕膜化

BackgroundRecurrent pregnancy loss (RPL), defined as 3 or more consecutive miscarriages, is widely attributed either to repeated chromosomal instability in the conceptus or to uterine factors that are

NIAID Data Ecosystem30

Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach

子宫内膜蜕膜化

性激素受体功能

The endometrial response to progesterone is mediated by the classical and non-classical progesterone receptors. We previously demonstrated that PGRMC1 is critical for endometrial function, embryo impl

NIAID Data Ecosystem50

Evolutionary transcriptomics of Eutherian gene expression gains and the origins of decidualization [Set 5]

子宫内膜蜕膜化

转录因子功能

We used human endometrial stromal fibroblast cell line to perform an siRNA knockdown coupled with RNA-seq screen of a series of transcription factors that gained expression in the endometrial tissue o

NIAID Data Ecosystem40

PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells

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